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Perfluoro-1,3-dim...
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(2R,3R,4S,5R)-2-(...
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Parameters
Properties | |
Properties | 【熔点 】60-62 °C(lit.)【闪点 】>230 °F【储存条件 】−20°C |
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Specification And Standard | |
Production And Usage | |
Production process | (R,S)-2-Hydroxyhexanoic acid (1h): General procedure for the preparation of alpha-hydroxycarboxylic acids (GP1): In a round bottom flask, 100 mmol alpha-amino acid was dissolved in 196 mL (200 mmol) of 1 N sulfuric acid. The solution was cooled to 0 degC and added with a cooled solution of 13.8 g (200 mmol) sodium nitrite in 30 mL water. The reaction mixture was stirred for 3 hours at 0 degC and then at rt overnight. Thereafter, the solution was heated for 20 min to 60 degC and after cooling extracted with diethyl ether (3 x 100 mL). The organic phase was separated, dried over Na2SO4 and the solvent was removed under vacuum. The product was further used without additional cleaning. From 13.2 g (100 mmol) D,L-norleucine in 196 mL (200 mmol) of 1 N H2SO4 and 13.8 g (200 mmol) of NaNO2, according to GP1, (R,S)-2-hydroxyhexanoic acid was obtained as a yellow oil. The compound was used without further purification. Yield: 10.44 g (79 mmol, 79 %). |
Packing And Storage | |
Safety | |
Spectrum And References | |
Contact Salesman | |
Buy reagents | 400-808-6996 |
Update | 20200220marketing |