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![ent-[Amyloid β-Protein (20-16)]-β-Ala-D-Lys(ent-[Amyloid β-Protein (16-20)]) trifluoroacetate salt](http://www.chemvia.com/images/goods/20181212/85da02a54c97f953.png)
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![ent-[Amyloid β-Protein (20-16)]-β-Ala-D-Lys(ent-[Amyloid β-Protein (16-20)]) trifluoroacetate salt](http://www.chemvia.com/images/goods/20181212/446a34ce9a3289e0.png)
| ent-[Amyloid β-Protein (20-16)]-β-Ala-D-Lys(ent-[Amyloid β-Protein (16-20)]) trifluoroacetate salt | ||
| Catalog Number | 335P78 | |
| Three Letter Code | H-D-Phe-D-Phe-D-Val-D-Leu-D-Lys-β-Ala-D-Lys(D-Lys-D-Leu-D-Val-D-Phe-D-Phe-H)-OH trifluoroacetate salt | |
| One Letter Code | ffvlk-β-Ala-D-Lys(klvff)-OH trifluoroacetate salt | |
| Synonyms | ent-[retro-Amyloid β-Protein (16-20)]-β-Ala-D-Lys(ent-[Amyloid β-Protein (16-20)]), (ffvlk)₂(βA)k (tandem dimer) | |
| Molecular Formula | C₇₉H₁₁₉N₁₅O₁₃ | |
| Relative Molecular Mass | 1486.91 | |
| CAS Registry Number | 1426174-31-3 | |
| Source | Synthetic | |
| Storage Conditions | -20 ± 5 °C | |
| Areas of Interest | Alzheimer's Disease | |
| Details | ||
| This all-D peptide contains two retro-inverso peptide klvff motifs of KLVFF (H-3682) corresponding to amino acids 16 to 20 of amyloid β-protein. The tandem dimer retro-inverso peptide showed about a 100-fold higher binding affinity (Kd = 1.3 · 10⁻² µM) for amyloid β-protein (1-40) fibrils than KLVFF (Kd = 1.1 ± 0.3 µM). It was also found to be more effective in preventing ordered fibril formation than the parent peptide KLVFF as judged by its increased ability to inhibit thioflavin T binding to β-sheet structures. | ||
| 报价或需更多信息请发邮件至：alex@hanhonggroup.com， 我们一定在第一时间回复您！ | ||
Parameters
| Properties | |
| Properties | 白色结晶粉末。 |
|---|---|
| Toxicity information | 仅用于科学研究。 |
| Specification And Standard | |
| SPEC1 | 根据客户的要求提供从60%至98%不同HPLC纯度的产品。 |
| Production And Usage | |
| Production process | SPPS固相法化学合成。 |
| Application | Alzheimer's Disease |
| Packing And Storage | |
| Packing | 冷存管，根据客户要求提供每管不同数量的包装。 |
| Storage | -20 ± 5 °C低温避光保存。 |
| Safety | |
| Spectrum And References | |
| 1H NMR | 根据客户的要求提供，但需额外检测费用。 |
| 13C NMR | 根据客户的要求提供，但需额外检测费用。 |
| MS | 发货时这个产品的MS，HPLC图谱及质检报告将一并提供。 |
| Contact Salesman | |
| Buy reagents | 邮箱alex@hanhonggroup.com, 手机：19961912513（微信同号） |
| Buy Bulk | 请联系alex@hanhonggroup.com |
