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FSL-1-FLAG trifluoroacetate salt | |
Catalog Number | 335P602 |
Three Letter Code | H-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys-OH trifluoroacetate salt |
One Letter Code | Pam₂CGDPKHPKSFDYKDDDDK |
Synonyms | Fibroblast Stimulating Lipopeptide 1 FLAG-tag |
Molecular Formula | C₁₂₅H₁₉₈N₂₄O₃₇S |
Relative Molecular Mass | 2661.15 |
Source | Synthetic |
Storage Conditions | -20 ± 5 °C |
Areas of Interest | Immunomodulating Agents |
Details | The lipopeptide FSL-1, synthesized on the basis of the N-terminal structure of a M. salivarium lipoprotein, is capable of inducing the cell surface expression of ICAM-1 in human gingival fibroblasts. It furthermore revealed an activity to induce production of monocyte chemoattractant protein 1, interleukin-6 (IL-6), and IL-8. FSL-1 also activated macrophages to produce tumor necrosis factor alpha. Overall, results by Okusawa and coworkers suggest that the diacylglyceryl and the peptide portions of FSL-1 are indispensable for the expression of biological activities and for the recognition by Toll-like receptors 2 and 6. Furthermore, the same authors conclude that the recognition of FSL-1 by Toll-like receptors 2 and 6 apparently is hydrophobic. |
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Parameters
Properties | |
Properties | 白色结晶粉末。 |
---|---|
Toxicity information | 仅用于科学研究。 |
Specification And Standard | |
SPEC1 | 根据客户的要求提供从60%至98%不同HPLC纯度的产品。 |
Production And Usage | |
Production process | SPPS固相法化学合成。 |
Application | Immunomodulating Agents |
Packing And Storage | |
Packing | 冷存管,根据客户要求提供每管不同数量的包装。 |
Storage | -20 ± 5 °C低温避光保存。 |
Safety | |
Spectrum And References | |
1H NMR | 根据客户的要求提供,但需额外检测费用。 |
13C NMR | 根据客户的要求提供,但需额外检测费用。 |
MS | 发货时这个产品的MS,HPLC图谱及质检报告将一并提供。 |
Contact Salesman | |
Buy reagents | 请联系alex@hanhonggroup.com |
Buy Bulk | 请联系alex@hanhonggroup.com |