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Myristoyl-(Lys¹²·²⁷·²⁸)-VIP-Gly-Gly-Thr (free acid) trifluoroacetate salt | |
Catalog Number | 335P580 |
Three Letter Code | Myristoyl-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Lys-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Lys-Lys-Gly-Gly-Thr-OH trifluoroacetate salt |
One Letter Code | Myristoyl-HSDAVFTDNYTKLRKQMAVKKYLNSIKKGGT |
Synonyms | PG 99-465 |
Molecular Formula | C₁₇₁H₂₈₃N₄₅O₄₇S |
Relative Molecular Mass | 3753.47 |
Source | Synthetic |
Storage Conditions | -20 ± 5 °C |
Areas of Interest | Cancer Research |
Details | PG 99-465 is a high affinity, selective VPAC2 receptor antagonist. It exhibited a 100-fold preference for the VPAC2 over the VPAC1 receptor. The compound showed partial agonistic activity on the VPAC1 receptor and was inactive on the VPAC2 receptor transfected in CHO cells, as well as on naturally expressed human VPAC2 receptors in the SUP T1 cell line. Dickson et al. observed an agonistic effect of PG99-465 on the human VPAC1 and PAC1 receptors. When applied singly, PG99-465 increased [cAMP](i) at all three hVPAC/PAC receptor subtypes. |
报价或需更多信息请发邮件至:alex@hanhonggroup.com, 我们一定在第一时间回复您! |
Parameters
Properties | |
Properties | 白色结晶粉末。 |
---|---|
Toxicity information | 仅用于科学研究。 |
Specification And Standard | |
SPEC1 | HPLC纯度: >95% |
Production And Usage | |
Production process | SPPS固相法化学合成。 |
Application | Cancer Research |
Packing And Storage | |
Packing | 冷存管,根据客户要求提供每管不同数量的包装。 |
Storage | -20 ± 5 °C低温避光保存。 |
Safety | |
Spectrum And References | |
1H NMR | 根据客户的要求提供,但需额外检测费用。 |
13C NMR | 根据客户的要求提供,但需额外检测费用。 |
MS | 发货时这个产品的MS,HPLC图谱及质检报告将一并提供。 |
Contact Salesman | |
Buy reagents | 邮箱alex@hanhonggroup.com, 手机:19961912513(微信同号) |
Buy Bulk | 请联系alex@hanhonggroup.com |