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Toxin GaTx1 trifluoroacetate salt | |
Catalog Number | 335P567 |
Three Letter Code | H-Cys-Gly-Pro-Cys-Phe-Thr-Thr-Asp-His-Gln-Met-Glu-Gln-Lys-Cys-Ala-Glu-Cys-Cys-Gly-Gly-Ile-Gly-Lys-Cys-Tyr-Gly-Pro-Gln-Cys-Leu-Cys-Asn-Arg-NH₂ trifluoroacetate salt(Disulfide bonds between Cys¹ and Cys¹⁸/Cys⁴ and Cys²⁵/Cys¹⁵ and Cys³⁰/Cys¹⁹ and Cys³²) |
One Letter Code | CGPCFTTDHQMEQKCAECCGGIGKCYGPQCLCNR-NH₂ |
Molecular Formula | C₁₄₇H₂₂₄N₄₆O₄₇S₉ |
Relative Molecular Mass | 3676.27 |
CAS Registry Number | 1926163-15-6 |
Source | Synthetic |
Storage Conditions | -20 ± 5 °C |
Areas of Interest | Ion Channel Modulating Agents |
Details | GaTx1 is a component of the venom of the yellow scorpion (Leiurus quinquestriatus hebraeus). The highly bridged 34-peptide, a chloride channel ligand, potently and reversibly inhibits cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels when the channels are in the interburst closed state. Since the toxin inhibits CFTR only when applied to the cytoplasmic side, it is unlikely that CFTR represents the native target. Manufactured and sold under license from Georgia Tech Research Corporation, USA; patent WO/2007/137163 (PCT/US2007/069243). |
报价或需更多信息请发邮件至:alex@hanhonggroup.com, 我们一定在第一时间回复您! |
Parameters
Properties | |
Properties | 白色结晶粉末。 |
---|---|
Toxicity information | 仅用于科学研究。 |
Specification And Standard | |
SPEC1 | HPLC纯度: >95% |
Production And Usage | |
Production process | SPPS固相法化学合成。 |
Application | Ion Channel Modulating Agents |
Packing And Storage | |
Packing | 冷存管,根据客户要求提供每管不同数量的包装。 |
Storage | -20 ± 5 °C低温避光保存。 |
Safety | |
Spectrum And References | |
1H NMR | 根据客户的要求提供,但需额外检测费用。 |
13C NMR | 根据客户的要求提供,但需额外检测费用。 |
MS | 发货时这个产品的MS,HPLC图谱及质检报告将一并提供。 |
Contact Salesman | |
Buy reagents | 邮箱alex@hanhonggroup.com, 手机:19961912513(微信同号) |
Buy Bulk | 请联系alex@hanhonggroup.com |