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H-Glu-Leu-Asp-[(2R,4S,5S)-5-amino-4-hydroxy-2,7-dimethyl-octanoyl]-Ala-Glu-Phe-OH | |
Catalog Number | 335P505 |
Three Letter Code | H-Glu-Leu-Asp-[(2R,4S,5S)-5-amino-4-hydroxy-2,7-dimethyl-octanoyl]-Ala-Glu-Phe-OH |
One Letter Code | ELD[(2R,4S,5S)-5-amino-4-hydroxy-2,7-dimethyl-octanoyl]AEF |
Molecular Formula | C₄₂H₆₅N₇O₁₅ |
Relative Molecular Mass | 908.02 |
CAS Registry Number | 1349991-28-1 |
Source | Synthetic |
Storage Conditions | -20 ± 5 °C |
Areas of Interest | Alzheimer's Disease |
Details | Glu-Leu-Asp-Leu-psi[CHOH-CH₂]-Ala-Ala-Glu-Phe (ELDL-psi[CHOH-CH₂]-AAEF), a potent inhibitor for human brain memapsin-2 (β-secretase) with a Ki-value of 0.3 nM. The hydroxyethylene isostere of the Leu-Ala motif functions as a mimic of the transition state. |
报价或需更多信息请发邮件至:alex@hanhonggroup.com, 我们一定在第一时间回复您! |
Parameters
Properties | |
Properties | 白色结晶粉末。 |
---|---|
Toxicity information | 仅用于科学研究。 |
Specification And Standard | |
SPEC1 | HPLC纯度: >95% |
Production And Usage | |
Production process | SPPS固相法化学合成。 |
Application | Alzheimer's Disease |
Packing And Storage | |
Packing | 冷存管,根据客户要求提供每管不同数量的包装。 |
Storage | -20 ± 5 °C低温避光保存。 |
Safety | |
Spectrum And References | |
1H NMR | 根据客户的要求提供,但需额外检测费用。 |
13C NMR | 根据客户的要求提供,但需额外检测费用。 |
MS | 发货时这个产品的MS,HPLC图谱及质检报告将一并提供。 |
Contact Salesman | |
Buy reagents | 邮箱alex@hanhonggroup.com, 手机:19961912513(微信同号) |
Buy Bulk | 请联系alex@hanhonggroup.com |