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| Fibronectin Fragment (1377-1388) | |
| Catalog Number | 335P318 |
| Three Letter Code | H-His-Ser-Arg-Asn-Ser-Ile-Thr-Leu-Thr-Asn-Leu-Thr-OH |
| One Letter Code | HSRNSITLTNLT |
| Molecular Formula | C₅₆H₉₇N₁₉O₂₀ |
| Relative Molecular Mass | 1356.5 |
| CAS Registry Number | 162257-99-0 |
| Source | Synthetic |
| Storage Conditions | -20 ± 5 °C |
| Areas of Interest | Adhesion Molecules & Extracellular Matrix Proteins| Cardiovascular System & Diseases| Hematology |
| Details | Fibronectin Fragment (1377-1388) inhibited fibronectin binding to the platelet membrane glycoprotein (GP) IIb/IIIa by interacting directly with this receptor, with an IC₅₀ of about 104 µM. HSRNSITLTNLT also inhibited the binding of fibrinogen to GPIIb/IIIa, as well as platelet aggregation. This indicates that this peptide derived from the cell binding domain of fibronectin comprises an RGD-independent GPIIb/IIIa binding site localized within the residues His¹³⁷⁷ and Ile¹³⁸². |
| 报价或需更多信息请发邮件至：alex@hanhonggroup.com， 我们一定在第一时间回复您！ | |
Parameters
| Properties | |
| Properties | 白色结晶粉末。 |
|---|---|
| Toxicity information | 仅用于科学研究。 |
| Specification And Standard | |
| SPEC1 | HPLC纯度: >95% |
| Production And Usage | |
| Production process | SPPS固相法化学合成。 |
| Application | Adhesion Molecules & Extracellular Matrix Proteins| Cardiovascular System & Diseases| Hematology |
| Packing And Storage | |
| Packing | 冷存管，根据客户要求提供每管不同数量的包装。 |
| Storage | -20 ± 5 °C低温避光保存。 |
| Safety | |
| Spectrum And References | |
| 1H NMR | 根据客户的要求提供，但需额外检测费用。 |
| 13C NMR | 根据客户的要求提供，但需额外检测费用。 |
| MS | 发货时这个产品的MS，HPLC图谱及质检报告将一并提供。 |
| Contact Salesman | |
| Buy reagents | 邮箱alex@hanhonggroup.com, 手机：19961912513（微信同号） |
| Buy Bulk | 请联系alex@hanhonggroup.com |
