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| CRF (6-33) (human, rat) | |
| Catalog Number | 335P212 |
| Three Letter Code | H-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-OH |
| One Letter Code | ISLDLTFHLLREVLEMARAEQLAQQAHS |
| Molecular Formula | C₁₄₁H₂₃₁N₄₁O₄₃S |
| Relative Molecular Mass | 3220.7 |
| CAS Registry Number | 120066-38-8 |
| Source | Synthetic |
| Storage Conditions | -20 ± 5 °C |
| Areas of Interest | Alzheimer's Disease |
| Details | This CRF fragment may have two different beneficial effects in Alzheimer's disease (AD). First CRF (6-33) dissociates CRF from the CRF-binding protein and may therefore be able to restore the dramatic reduction of free CRF content in AD. Second this fragment shows cognition-enhancing properties in animal models of learning and memory, without the characteristic anxiogenic effects of CRF receptor agonists, and may therefore be useful in the treatment of memory deficits seen in AD. |
| 报价或需更多信息请发邮件至：alex@hanhonggroup.com， 我们一定在第一时间回复您！ | |
Parameters
| Properties | |
| Properties | 白色结晶粉末。 |
|---|---|
| Toxicity information | 仅用于科学研究。 |
| Specification And Standard | |
| SPEC1 | HPLC纯度: >95% |
| Production And Usage | |
| Production process | SPPS固相法化学合成。 |
| Application | Alzheimer's Disease |
| Packing And Storage | |
| Packing | 冷存管，根据客户要求提供每管不同数量的包装。 |
| Storage | -20 ± 5 °C低温避光保存。 |
| Safety | |
| Spectrum And References | |
| 1H NMR | 根据客户的要求提供，但需额外检测费用。 |
| 13C NMR | 根据客户的要求提供，但需额外检测费用。 |
| MS | 发货时这个产品的MS，HPLC图谱及质检报告将一并提供。 |
| Contact Salesman | |
| Buy reagents | 邮箱alex@hanhonggroup.com, 手机：19961912513（微信同号） |
| Buy Bulk | 请联系alex@hanhonggroup.com |
