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(D-Arg¹,D-Trp⁵·⁷·⁹,Leu¹¹)-Substance P | |
Catalog Number | 303P06 |
Three Letter Code | H-D-Arg-Pro-Lys-Pro-D-Trp-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH₂ |
One Letter Code | rPKPwQwFwLL-NH₂ |
Synonyms | [DArg1, DTrp5,7,9, Leu11] Substance P |
Molecular Formula | C₈₁H₁₁₀N₂₀O₁₂ |
Relative Molecular Mass | 1555.89 |
CAS Registry Number | 122481-75-8 |
Source | Synthetic |
Storage Conditions | -20 ± 5 °C |
Areas of Interest | Cancer Research |
Details | This substance P analog is a very potent broad-spectrum neuropeptide inhibitor for small cell lung cancer (SCLC) cell growth in vitro (IC₅₀ = 5 µM). Moreover it potently inhibited signal transduction pathways in vitro and significantly delayed the growth of an SCLC xenograft in vivo. It could therefore be of therapeutic value in SCLC. |
报价或需更多信息请发邮件至:alex@hanhonggroup.com, 我们一定在第一时间回复您! |
Parameters
Properties | |
Properties | 白色结晶粉末。 |
---|---|
Toxicity information | 仅用于科学研究。 |
Specification And Standard | |
SPEC1 | HPLC纯度: >95% |
Production And Usage | |
Production process | SPPS固相法化学合成。 |
Application | Cancer Research |
Packing And Storage | |
Packing | 冷存管,根据客户要求提供每管不同数量的包装。 |
Storage | -20 ± 5 °C低温避光保存。 |
Safety | |
Spectrum And References | |
1H NMR | 根据客户的要求提供,但需额外检测费用。 |
13C NMR | 根据客户的要求提供,但需额外检测费用。 |
MS | 发货时这个产品的MS,HPLC图谱及质检报告将一并提供。 |
Contact Salesman | |
Buy reagents | 邮箱alex@hanhonggroup.com, 手机:19961912513(微信同号) |
Buy Bulk | 请联系alex@hanhonggroup.com |