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| (Lys⁸-psi(CH₂NH)Lys⁹)-Neurotensin (8-13) | |
| Catalog Number | 21P11 |
| Three Letter Code | H-Lys-psi(CH₂NH)Lys-Pro-Tyr-Ile-Leu-OH |
| One Letter Code | K-psi(CH₂NH)KPYIL |
| Synonyms | JMV 449, (Lys8-acetyl-Lys9)-Neurotensin (8-13) |
| Molecular Formula | C₃₈H₆₆N₈O₇ |
| Relative Molecular Mass | 746.99 |
| CAS Registry Number | 139026-66-7 |
| Source | Synthetic |
| Storage Conditions | -20 ± 5 °C |
| Areas of Interest | Cancer Research |
| Details | Replacement of the Lys⁸-Lys⁹ peptide bond by the CH₂NH bond produced an analog with quite interesting pharmacological properties. The degradation-resistant peptide analog Lys-psi(CH2NH)Lys-Pro-Tyr-Ile-Leu (JMV-449) was the most active in the binding and biological assays. JMV-449 exhibited higher binding and biological potencies than neurotensin. JMV449 was also about 10 times more potent than neurotensin (8-13) in the bioassay, whereas both peptides were equipotent in the binding assay. |
| 报价或需更多信息请发邮件至：alex@hanhonggroup.com， 我们一定在第一时间回复您！ | |
Parameters
| Properties | |
| Properties | 白色结晶粉末。 |
|---|---|
| Toxicity information | 仅用于科学研究。 |
| Specification And Standard | |
| SPEC1 | HPLC纯度: >95% |
| Production And Usage | |
| Production process | SPPS固相法化学合成。 |
| Application | Cancer Research |
| Packing And Storage | |
| Packing | 冷存管，根据客户要求提供每管不同数量的包装。 |
| Storage | -20 ± 5 °C低温避光保存。 |
| Safety | |
| Spectrum And References | |
| 1H NMR | 根据客户的要求提供，但需额外检测费用。 |
| 13C NMR | 根据客户的要求提供，但需额外检测费用。 |
| MS | 发货时这个产品的MS，HPLC图谱及质检报告将一并提供。 |
| Contact Salesman | |
| Buy reagents | 邮箱alex@hanhonggroup.com, 手机：19961912513（微信同号） |
| Buy Bulk | 请联系alex@hanhonggroup.com |
