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| LL-37 trifluoroacetate salt | ||
| Catalog Number | 194P02 | |
| Three Letter Code | H-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH trifluoroacetate salt | |
| One Letter Code | LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES | |
| Synonyms | Antibacterial Protein LL-37 (human), LL37, CAMP | |
| Molecular Formula | C₂₀₅H₃₄₀N₆₀O₅₃ | |
| Relative Molecular Mass | 4493.33 | |
| CAS Registry Number | 154947-66-7 | |
| Source | Synthetic | |
| Storage Conditions | -20 ± 5 °C | |
| Areas of Interest | Angiogenesis| Antimicrobial & Antiviral Peptides| Cancer Research| Inflammation Research | |
| Details | ||
| LL-37 is an antimicrobial peptide with angiogenic activity. It corresponds to the C-terminal sequence (134-170) of the human cathelicidin antimicrobial protein hCAP18/LL-37 and is extracellularly released from hCAP18/LL-37 by proteolytic processing. hCAP18/LL-37 is an effector of the innate immune system and is expressed in leukocytes and epithelial cells where it is upregulated in association with inflammation and injury. An overexpression of hCAP18/LL-37 in a series of breast carcinomas could be demonstrated. LL-37 has been suggested to stimulate epithelial cell proliferation partially through formyl peptide receptor-like 1 (FPRL1) since blocking the receptor with pertussis toxin decreased the proliferative effect of LL-37 by approximately 50 %. | ||
| 报价或需更多信息请发邮件至：alex@hanhonggroup.com， 我们一定在第一时间回复您！ | ||
Parameters
| Properties | |
| Properties | 白色结晶粉末。 |
|---|---|
| Toxicity information | 仅用于科学研究。 |
| Specification And Standard | |
| SPEC1 | 根据客户的要求提供从60%至98%不同HPLC纯度的产品。 |
| Production And Usage | |
| Production process | SPPS固相法化学合成。 |
| Application | Angiogenesis| Antimicrobial & Antiviral Peptides| Cancer Research| Inflammation Research |
| Packing And Storage | |
| Packing | 冷存管，根据客户要求提供每管不同数量的包装。 |
| Storage | -20 ± 5 °C低温避光保存。 |
| Safety | |
| Spectrum And References | |
| 1H NMR | 根据客户的要求提供，但需额外检测费用。 |
| 13C NMR | 根据客户的要求提供，但需额外检测费用。 |
| MS | 发货时这个产品的MS，HPLC图谱及质检报告将一并提供。 |
| Contact Salesman | |
| Buy reagents | 邮箱alex@hanhonggroup.com, 手机：19961912513（微信同号） |
| Buy Bulk | 请联系alex@hanhonggroup.com |
