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| Uroguanylin Topoisomer B (human) trifluoroacetate salt | |
| Catalog Number | 159P05 |
| Three Letter Code | H-Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu-OH trifluoroacetate salt(Disulfide bonds between Cys⁴ and Cys¹²/Cys⁷ and Cys¹⁵) |
| One Letter Code | NDDCELCVNVACTGCL |
| Synonyms | UGN Topoisomer B (human) |
| Molecular Formula | C₆₄H₁₀₂N₁₈O₂₆S₄ |
| Relative Molecular Mass | 1667.88 |
| Source | Synthetic |
| Storage Conditions | -20 ± 5 °C |
| Areas of Interest | Gastrointestinal Research| Obesity Research |
| Details | Short peptides containing two disulfide bridges can form interconvertible topoisomers with the same disulfide connectivity. In case of uroguanylin (UGN), both are relatively stable and can be separated, and interconversion is slow. The topoisomers differ in biological activity: The UGN A topomer potently activates the guanylate cyclase C receptor found primarily in the intestine. The B topomer is a very weak agonist of this receptor. Moss et al. could show that UGN B has potent natriuretic activity in the kidney. |
| 报价或需更多信息请发邮件至：alex@hanhonggroup.com， 我们一定在第一时间回复您！ | |
Parameters
| Properties | |
| Properties | 白色结晶粉末。 |
|---|---|
| Toxicity information | 仅用于科学研究。 |
| Specification And Standard | |
| SPEC1 | HPLC纯度: >95% |
| Production And Usage | |
| Production process | SPPS固相法化学合成。 |
| Application | Gastrointestinal Research| Obesity Research |
| Packing And Storage | |
| Packing | 冷存管，根据客户要求提供每管不同数量的包装。 |
| Storage | -20 ± 5 °C低温避光保存。 |
| Safety | |
| Spectrum And References | |
| 1H NMR | 发货时这个产品的MS，HPLC图谱及质检报告将一并提供。 |
| 13C NMR | 发货时这个产品的MS，HPLC图谱及质检报告将一并提供。 |
| MS | 根据客户的要求提供，但需额外检测费用。 |
| Contact Salesman | |
| Buy reagents | 邮箱alex@hanhonggroup.com, 手机：19961912513（微信同号） |
| Buy Bulk | 请联系alex@hanhonggroup.com |
