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Retrocyclin-1 trifluoroacetate salt

HPLC >95%

  • Commodity number:103P07
  • Goods number:103P07
  • Abbreviation: Cyclo(-GICRCICGRGICRCICGR)
  • CAS: 724760-19-4
  • MF: C₇₄H₁₂₈N₃₀O₁₈S₆
  • Synonyms: Cyclo(-Gly-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg-Gly-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg) trifluoroacetate salt(Disulfide bonds between Cys³ and Cys¹⁶/Cys⁵ and Cys¹⁴/Cys⁷ and Cys¹²)
  • MW: 1918.42
  • Original price: ¥0.00
  • Present price: ¥0.00
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Retrocyclin-1 trifluoroacetate salt
Catalog Number 103P07 
Three Letter Code Cyclo(-Gly-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg-Gly-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg) trifluoroacetate salt(Disulfide bonds between Cys³ and Cys¹⁶/Cys⁵ and Cys¹/Cys⁷ and Cys¹²)
One Letter Code Cyclo(-GICRCICGRGICRCICGR)
Synonyms RC-100
Molecular Formula    C₇H₁₂₈N₀O₈S₆
Relative Molecular Mass  1918.42
CAS Registry Number 724760-19-4
Source   Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest  Antimicrobial & Antiviral Peptides|
Infectious Disease
Details
The theta-defensin retrocyclin-1, also called RC-100, is a circular octadecapeptide containing an internal trisulfide ladder. Besides its antimicrobial activity, retrocyclin-1 has a remarkable ability to protect human cells in vitro from infection by T- and M-tropic strains of HIV-1. Its effectiveness against HIV-1 results from the prevention of viral entry, and is correlated with its ability to recognize and bind with high affinity to glycoproteins and glycolipids implicated in HIV-1 entry, such as gp120 (KD = 35.4 nM), CD4 (KD = 31 nM), and galactosylceramide (KD = 24.1 nM). Retrocyclin represents a new class of small molecule HIV-1 entry inhibitors. 
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Parameters

Properties
Properties白色结晶粉末。
Toxicity information仅用于科学研究。
Specification And Standard
SPEC1根据客户的要求提供从60%至98%不同HPLC纯度的产品。
Production And Usage
Production processSPPS固相法化学合成。
ApplicationAntimicrobial & Antiviral Peptides| Infectious Disease
Packing And Storage
Packing冷存管,根据客户要求提供每管不同数量的包装。
Storage-20 ± 5 °C低温避光保存。
Safety
Spectrum And References
1H NMR根据客户的要求提供,但需额外检测费用。
13C NMR根据客户的要求提供,但需额外检测费用。
MS发货时这个产品的MS,HPLC图谱及质检报告将一并提供。
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