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Retrocyclin-1 trifluoroacetate salt | ||
Catalog Number | 103P07 | |
Three Letter Code | Cyclo(-Gly-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg-Gly-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg) trifluoroacetate salt(Disulfide bonds between Cys³ and Cys¹⁶/Cys⁵ and Cys¹⁴/Cys⁷ and Cys¹²) | |
One Letter Code | Cyclo(-GICRCICGRGICRCICGR) | |
Synonyms | RC-100 | |
Molecular Formula | C₇₄H₁₂₈N₃₀O₁₈S₆ | |
Relative Molecular Mass | 1918.42 | |
CAS Registry Number | 724760-19-4 | |
Source | Synthetic | |
Storage Conditions | -20 ± 5 °C | |
Areas of Interest | Antimicrobial & Antiviral Peptides| Infectious Disease | |
Details | ||
The theta-defensin retrocyclin-1, also called RC-100, is a circular octadecapeptide containing an internal trisulfide ladder. Besides its antimicrobial activity, retrocyclin-1 has a remarkable ability to protect human cells in vitro from infection by T- and M-tropic strains of HIV-1. Its effectiveness against HIV-1 results from the prevention of viral entry, and is correlated with its ability to recognize and bind with high affinity to glycoproteins and glycolipids implicated in HIV-1 entry, such as gp120 (KD = 35.4 nM), CD4 (KD = 31 nM), and galactosylceramide (KD = 24.1 nM). Retrocyclin represents a new class of small molecule HIV-1 entry inhibitors. | ||
报价或需更多信息请发邮件至:alex@hanhonggroup.com, 我们一定在第一时间回复您! |
Parameters
Properties | |
Properties | 白色结晶粉末。 |
---|---|
Toxicity information | 仅用于科学研究。 |
Specification And Standard | |
SPEC1 | 根据客户的要求提供从60%至98%不同HPLC纯度的产品。 |
Production And Usage | |
Production process | SPPS固相法化学合成。 |
Application | Antimicrobial & Antiviral Peptides| Infectious Disease |
Packing And Storage | |
Packing | 冷存管,根据客户要求提供每管不同数量的包装。 |
Storage | -20 ± 5 °C低温避光保存。 |
Safety | |
Spectrum And References | |
1H NMR | 根据客户的要求提供,但需额外检测费用。 |
13C NMR | 根据客户的要求提供,但需额外检测费用。 |
MS | 发货时这个产品的MS,HPLC图谱及质检报告将一并提供。 |
Contact Salesman | |
Buy reagents | 邮箱alex@hanhonggroup.com, 手机:19961912513(微信同号) |
Buy Bulk | 请联系alex@hanhonggroup.com |